Abstract
It is proposed that sulfur be used as the oxidizing agent in the synthesis of 2-arylimidazopyridines from o-diaminopyridines and aromatic (heteroaromatic) aldehydes. Benzyl alcohols and benzylpyridinium salts can be used in place of aldehydes. 2-Phenylimidazopyridines are also formed in the thermal oxidation with sulfur of o-diaminopyridines with a benzyl substituent attached to the ring or exocyclic nitrogen atoms.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 639–645, May, 1987.
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Yutilov, Y.M., Shcherbina, L.I. Preparation of 2-aryl-substituted imidazo[4,5-b]pyridines and imidazo[4,5-c]pyridines. Chem Heterocycl Compd 23, 529–535 (1987). https://doi.org/10.1007/BF00476381
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DOI: https://doi.org/10.1007/BF00476381