Chemistry of Heterocyclic Compounds

, Volume 23, Issue 9, pp 990–992 | Cite as

Circular dichroism and configuration of (−)-1-methyl-1,2,3,4,tetrahydroisoquinoline

  • V. M. Potapov
  • V. M. Dem'yanovich
  • T. V. Skvortsova
Article
  • 56 Downloads

Abstract

In the CD (circular dichroism) spectra of (−)-1-methyl-1,2,3,4, tetrahydroisoquinoline, three CE (Cotton effects) are observed in the 300–200 nm region that are due to the absorption bands of the aromatic chromophore. The synthesis of this substance from (S)(−)-α-phenylethylamine and the CD spectra confirm its (S)-configuration.

Keywords

Organic Chemistry Absorption Band Circular Dichroism Cotton Effect Tetrahydroisoquinoline 

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Literature Cited

  1. 1.
    A. P. Orekhov, Chemistry of the Alkaloids [in Russian], Khimiya, Moscow, (1955), p. 270.Google Scholar
  2. 2.
    J. C. Craig and S. K. Roy, Tetrahedron, 21, 401 (1965).Google Scholar
  3. 3.
    A. R. Battersby, J. R. Bich, W. Klyne, J. P. Jennings, P. M. Scopes, and J. Vernengo, J. Chem. Soc., No. 3, 2239 (1965).Google Scholar
  4. 4.
    T. Kametani, H. Sugi, and S. Shiluya, Tetrahedron, 27, 2409 (1971).Google Scholar
  5. 5.
    J. C. Craig, S. Y. C. Lee, R. P. K. Chan, and I. J. F. Wang, J. Am. Chem. Soc., 99, 7996 (1977).Google Scholar
  6. 6.
    W. Leithe, Monatsh. Chem., 53–54, 952 (1929).Google Scholar
  7. 7.
    A. J. Meyers, L. M. Fluentes, and Y. Kubota, Tetrahedron, 40, 1361 (1984).Google Scholar
  8. 8.
    L. W. Deady, N. H. Pirzada, and R. D. Topsom, Chem. Commun., No. 15, 799 (1971).Google Scholar
  9. 9.
    V. M. Prostakov V. M. Dem'yanovich, and T. V. Skvortsova, Inventors Certificate 768177 (USSR); Byull. Izobret., No. 29, 264 (1985).Google Scholar
  10. 10.
    V. M. Potapov, V. M. Dem'yanovich, and V. I. Maleev, Zh. Org. Khim., 21, 1758 (1985).Google Scholar
  11. 11.
    J. W. Westly and B. Halpern, Gas Chromatography International 7th Symposium, Copenhagen; (London) 1969, p. 119.Google Scholar

Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • V. M. Potapov
    • 1
  • V. M. Dem'yanovich
    • 1
  • T. V. Skvortsova
    • 1
  1. 1.M. V. Lomonosov Moscow State UniversityMoscow

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