Abstract
The oxidation of trans-2,6-diethoxy-Δ 3-dihydropyran with perbenzoic acid gave a mixture of stereoisomeric epoxides, from which one individual isomer was isolated. The configuration and conformation of the epoxide obtained was established by PMR spectroscopy. 2,6-Diethoxy-3-hydroxy-4-dialkylaminotetrahydropyrans were obtained by the reaction of 2,6-diethoxy-3,4-epoxytetrahydropyran with dimethylamine and piperidine; the structural direction of the opening of the epoxide ring was studied by mass spectrometry.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 879–882, July, 1972.
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Kralinina, L.N., Kruglikova, R.I. & Unkovskii, B.V. Preparation of stereoisomeric functionally. Chem Heterocycl Compd 8, 796–799 (1972). https://doi.org/10.1007/BF00475204
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DOI: https://doi.org/10.1007/BF00475204