Abstract
In order to study the reaction mechanism of the catalytic intramolecular conversion of heterocycles [1–3] and to broaden the field of their application, we have studied the dehydration over Al2O3 of 1-amino-3-(α-tetrahydrofuryl) propane (I), 1-methylamino-1-(α-tetrahydrofuryl) propane (II), and 2-(3-hydroxy-1-propyl)-1-methylpyrrolidine (III), leading in all three cases to pyrrolizidine (IV).
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References
A. A. Ponomarev and I. M. Skvortsov, ZhOKh, 32, 97, 1962.
A. A. Ponomarev and I. M. Skvortsov, DAN, 148, 860, 1963.
I. M. Skvortsov, E. A. Zadumina, and A. A. Ponomarev, KhGS [Chemistry of Heterocyclic Compounds], 864, 1965.
Yu. K. Yur'ev, Uch. zap. MGU, 175, 159, 1956.
N. J. Leonard and W. E. Goode, J. Am. Chem. Soc, 72, 5404, 1950.
E. E. Schweizer and K. K. Light, J. Am. Chem. Soc, 86, 2963, 1964.
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Skvortsov, I.M., Mikhailov, G.D. A study of the reaction mechanism of the catalytic intramolecular conversion of heterocycles. Chem Heterocycl Compd 3, 874 (1967). https://doi.org/10.1007/BF00474898
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DOI: https://doi.org/10.1007/BF00474898