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Synthesis of 2, 6-derivatives of 1, 4-dioxane

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Stereoisomers of 6-halomethyl-2-hydroxymethyl-1, 4-dioxanes have been obtained via the cyclization of the monoallyl ether of glycerol. The stereoisomeric bromides differ considerably in their physical properties. The bromine atoms of the stereoisomers differ in their reactivity towards thiourea.

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References

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Zotov, S.B., Smirnov, V.V., Kvasnyuk-Mudryi, F.V. et al. Synthesis of 2, 6-derivatives of 1, 4-dioxane. Chem Heterocycl Compd 3, 872–873 (1967). https://doi.org/10.1007/BF00474897

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  • DOI: https://doi.org/10.1007/BF00474897

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