Chemistry of Heterocyclic Compounds

, Volume 28, Issue 7, pp 795–797 | Cite as

Synthesis of halogen substituted imidazo[4,5-e][1,4]diazepine-5,8-diones. Cyclic homologs of methylxanthines

  • É. I. Ivanov
  • G. D. Kalayanov
  • I. M. Yaroshchenko
Article
  • 39 Downloads

Abstract

Possible routes for synthesis of 2-haloimidazo[4,5-e][1,4]diazepines are discussed. Conditions for chlorination differ for homologs of caffeine, theophylline, and theobromine. For the caffeine homolog, both the 2-chloroand 2,6,6-trichloro products are obtained depending on the synthetic conditions

Keywords

Organic Chemistry Caffeine Theophylline Diones Halogen 

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Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • É. I. Ivanov
    • 1
  • G. D. Kalayanov
    • 1
  • I. M. Yaroshchenko
    • 1
  1. 1.A. V. Bogatskii Physicochemical InstituteUkrainian Academy of SciencesOdessa

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