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Chemistry of indole

XLIV. Formation of cyclic amides from nitriles of the indole and indolenine series

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Under the conditions of the Ritter reaction (sulfuric acid), indolylacetonitrile is converted to a tricyclic tactam of the pyrrolo[2,3-b]indole series. Depending on their structure and the reaction conditions, nitriles of the indolenine series form linear amides or cyclic lactams.

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Literature cited

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Authors and Affiliations

  1. M. V. Lomonosov Moscow State University, USSR

    A. N. Kost, N. B. Chernyshova, L. G. Yudin & V. I. Terenin

Authors
  1. A. N. Kost
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  2. N. B. Chernyshova
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  3. L. G. Yudin
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  4. V. I. Terenin
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Additional information

See [1] for communication XLIII.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1506–1511, November, 1975.

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Kost, A.N., Chernyshova, N.B., Yudin, L.G. et al. Chemistry of indole. Chem Heterocycl Compd 11, 1283–1287 (1975). https://doi.org/10.1007/BF00474455

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  • DOI: https://doi.org/10.1007/BF00474455

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