Abstract
It is shown that the reaction of 3-aminoacrolein with cyclic ketones of medium size can be used to synthesize inaccessible 2,3-polymethylenepyridines with polymethylene chains of 5, 6, 10, and 12 carbon atoms.
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E. Breitmeier and E. Bauer, Tetrahedron Lett., 38, 3291 (1970).
P. B. Terent'ev, Mass Spectrometry in Organic Chemistry [in Russian], Vysshaya Shkola, Moscow (1976), p. 128.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1649–1651, December, 1986.
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Matveeva, E.D., Tungusova, E.E., Bundel', Y.G. et al. Synthesis of 2,3-polymethylenepyridines from 3-aminoacrolein and cyclic ketones. Chem Heterocycl Compd 22, 1334–1336 (1986). https://doi.org/10.1007/BF00474354
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DOI: https://doi.org/10.1007/BF00474354