Chemistry of Heterocyclic Compounds

, Volume 22, Issue 12, pp 1291–1295 | Cite as

Alkylation of Β-dicarbonyl compounds by 1,2,3-trihalopropanes as a method for the preparation of Β-substituted furans

  • Sh. T. Akhmedov
  • N. S. Sadykhov
  • V. M. Ismailov
  • M. A. Akhundova
  • N. K. Sadovaya
  • F. N. Karimov
  • N. S. Zefirov
Article

Abstract

Alkylation of Β-dicarbonyl compounds by 1,2,3-trihalides leads to a readily separable mixture of mono- and dialkylation products, and under more rigorous conditions, to 3-substituted 2,4-dimethylfurans. A similar reaction with propargyl bromide leads to furans with a “normal” structure, namely, 2,5-dimethylfurans.

Keywords

Bromide Organic Chemistry Alkylation Furan Similar Reaction 

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Copyright information

© Plenum Publishing Corporation 1987

Authors and Affiliations

  • Sh. T. Akhmedov
    • 1
    • 2
  • N. S. Sadykhov
    • 1
    • 2
  • V. M. Ismailov
    • 1
    • 2
  • M. A. Akhundova
    • 1
    • 2
  • N. K. Sadovaya
    • 1
    • 2
  • F. N. Karimov
    • 1
    • 2
  • N. S. Zefirov
    • 1
    • 2
  1. 1.M. V. Lomonosov Moscow State UniversityMoscow
  2. 2.S. M. Kirov Azerbaidzhan State UniversityBaku

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