Abstract
Catalytic hydroamination of 1,2-bis-(hydroxymethyl)cyclohexane by aliphatic nitriles over a nickel catalyst yielded a series of N-alkyl-substituted octahydroisoindoles. Conditions for their synthesis were selected. The IR, PMR, and mass spectra and the probable mechanism of formation of these compounds are discussed.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1619–1622, December, 1990.
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Kozintsev, S.I., Zhavrid, A.S., Serzhanin, A.I. et al. Catalytic synthesis of N-alkyloctahydroisoindoles. Chem Heterocycl Compd 26, 1346–1348 (1990). https://doi.org/10.1007/BF00473961
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DOI: https://doi.org/10.1007/BF00473961