Chemistry of Heterocyclic Compounds

, Volume 7, Issue 2, pp 232–236 | Cite as

Kinetics of nucleophilic halogen exchange in 1-alkyl-2-(5′ -halo-2′- furyl) benzimidazoles

  • V. N. Novikov
  • V. Ts. Bukhaeva
  • F. T. Pozharskii
  • A. M. Simonov
Article
  • 27 Downloads

Abstract

The kinetics of the reaction of 1-alkyl-2-(5′-halo-2′-furyl)benzimidazoles and their corresponding quaternary salts with secondary aliphatic amines were studied. The effect on the activation parameters of this reaction of the nature of the halogen being replaced by the secondary amine residue, the presence of a positive charge on the imidazole ring, the character of the anion in the quaternary salts, and the remoteness of the reaction center from the activating grouping on the activation parameters of this reaction is discussed.

Keywords

Organic Chemistry Imidazole Reaction Center Positive Charge Halogen 

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Copyright information

© Consultants Bureau 1973

Authors and Affiliations

  • V. N. Novikov
    • 1
  • V. Ts. Bukhaeva
    • 1
  • F. T. Pozharskii
    • 1
  • A. M. Simonov
    • 1
  1. 1.Rostov-on-Don State UniversityUSSR

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