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Fresenius' Zeitschrift für analytische Chemie

, Volume 332, Issue 6, pp 627–629 | Cite as

Human albumin as a reference material for trace elements

  • F. S. Diver
  • D. Littlejohn
  • T. D. B. Lyon
  • G. S. Fell
Trace Elements

Summary

An investigation through interlaboratory comparison using different analytical techniques has been carried out in order to assess the suitability of a plasma protein solution as a source for a trace element reference material in clinical analysis. Reasonable agreement was obtained for a number of elements from the range studied: Al, Ba, Cr, Cu, Fe, Mg, Mn, Mo, Ni, Se, Sr, V and Zn. The techniques used included flame and furnace atomic absorption spectrometry (FAAS and ETA-AAS), furnace atomic emission spectrometry (ETA-AES), inductively coupled plasma atomic emission spectrometry (ICP-AES), inductively coupled plasma mass spectrometry (ICP-MS), and simultaneous multi-element atomic absorption spectrometry (SIMAAC). Results indicated that this plasma protein solution may prove useful as a source for a reference material covering trace element levels outwith the range found in normal human plasma.

Keywords

Furnace Reference Material Inductively Couple Plasma Mass Spectrometry Human Plasma Atomic Absorption Spectrometry 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Humanalbumin als Referenzmaterial für Spurenelemente

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Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • F. S. Diver
    • 1
  • D. Littlejohn
    • 1
  • T. D. B. Lyon
    • 2
  • G. S. Fell
    • 2
  1. 1.Department of Pure and Applied ChemistryUniversity of StrathclydeGlasgowScotland, UK
  2. 2.Department of Pathological BiochemistryRoyal InfirmaryGlasgowScotland, UK

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