Chemistry of Heterocyclic Compounds

, Volume 10, Issue 3, pp 358–361 | Cite as

Research on unsaturated azole derivatives

I. Synthesis and transformations of α,β-unsaturated acids in the azole series
  • I. I. Popov
  • A. M. Simonov
  • V. I. Mikhailov
  • N. A. Sil'vanovich


A number of esters of some β-(2-azolyl)acrylic acids were synthesized by means of the Wittig reaction and subjected to hydrolysis. The reaction of β-(1-methyl-2-benzimidazolyl)-acrylic acid and its derivatives with bromine was studied. It is shown that 1-methyl-2-ethynylbenzimidazole and 1,2-dimethylbenzimidazole are formed when methyl α-bromo-β-(1-methyl-2-benzimidazolyl)-acrylate is refluxed in sodium bicarbonate solution.


Sodium Methyl Ester Hydrolysis Organic Chemistry 
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Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • I. I. Popov
    • 1
  • A. M. Simonov
    • 1
  • V. I. Mikhailov
    • 1
  • N. A. Sil'vanovich
    • 1
  1. 1.Rostov State UniversityRostov-on-Don

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