Abstract
The corresponding 1-(6-substituted-9-purinyl)-2,2-diethoxyethanes were obtained by alkylation of 6-substituted purines with 1-bromo-2,2-diethoxyethane. Subsequent transformations of a large portion of the acetals gave 2-(6-substituted-9-purinyl) acetaldehydes, from which β-(6-substituted-9-purinyl)alanines were obtained by the cyanohydrin synthesis. The classification of the compounds as N(9)-substituted purine derivatives was proved by means of UV spectroscopy.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1561–1566, November, 1972.
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Lidak, M.Y., Shluke, Y.Y. & Poritere, S.E. Synthesis of β-(9-purinyl)alanines. Chem Heterocycl Compd 8, 1411–1416 (1972). https://doi.org/10.1007/BF00471886
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DOI: https://doi.org/10.1007/BF00471886