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Chemistry of Heterocyclic Compounds

, Volume 8, Issue 11, pp 1380–1382 | Cite as

Azaindole derivatives

XLI. Synthesis of 3-substituted 5-azaindoles
  • L. N. Yakhontov
  • E. I. Lapan
Article
  • 35 Downloads

Abstract

Electrophilic substitution reactions — cyanomethylation, bromination, nitration, and the Mannich reaction- in the 5-azaindole series were studied. It is shown that, despite the literature data, 5-azaindole behaves like the isomeric 4- and 7-azaindoles in these reactions. Conditions that make it possible to synthesize various 3-substituted 5-azaindoles in high yields were found.

Keywords

Organic Chemistry Nitration Substitution Reaction Electrophilic Substitution Mannich Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1974

Authors and Affiliations

  • L. N. Yakhontov
    • 1
  • E. I. Lapan
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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