Abstract
The alkylation of benzimidazole and its derivatives with propargyl bromide was studied. 1-(2′-Propynyl)benzimidazoles are readily formed in liquid ammonia in the presence of sodium amide. The alkylation of 1-ethyl-2-aminobenzimidazole leads to a mixture of 2-(N-mono)- and 2-(N,N-2′-propynyl)amino-1-ethylbenzimidazoles.
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See [1] for communication XXX.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 551–552, April, 1973.
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Popov, I.I., Tkachenko, P.V. & Simonov, A.M. Benzimidazole derivatives. Chem Heterocycl Compd 9, 507–509 (1973). https://doi.org/10.1007/BF00471539
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DOI: https://doi.org/10.1007/BF00471539