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Synthesis of 1-(4-bromo-1-naphthyl)-dihydrouracil and some of its transformations

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

1-(4-Bromo-1-naphthyl)dihydrouracil, which is also obtained from 1-(4-bromo-1-naphthyl)-β-alanine, is formed by the bromination of 1-(1-naphthyl)dihydrouracil. Hydrogenation of 1-(4-bromo-1-naphthyl)dihydrouracil with lithium aluminum hydride yields either 1-(1-naphthyl)-2-oxohexahydropyrimidine or 1-(4-bromo-1-naphthyl)-2-oxohexahydropyrimidine, depending on the solvent used. 1-(4-Bromo-1-naphthyl)-2-oxohexahydropyrimidine is formed by the bromination of 1-(1-naphthyl)-2-oxohexahydropyrimidine.

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Literature cited

  1. N. W. Gabel and S. B. Binkley, J. Org. Chem., 23, 644 (1958).

    Google Scholar 

  2. R. S. Baltrushis and I. I. Marioshyus, Khim. Geterotsikl. Soedin., 954 (1968).

  3. R. S. Baltrushis and I. I. Marioshyus, USSR Author's Certificate No. 197,595; Byull. Izobr., No. 13 (1967).

  4. R. S. Baltrushis, I. I. Marioshyus, and Z. G. Beresnevichyus, USSR Author's Certificate No. 232,269; Byull. Izobr., No. 1 (1969).

  5. R. Baltrushis and I. Marioshyus, Khim. Geterotsikl. Soedin., No. 1, 120 (1969).

    Google Scholar 

  6. F. J. Marshall, J. Am. Chem. Soc., 78, 3696 (1956).

    Google Scholar 

  7. Z. G. Beresnevichyus, I. Marioshyus, and R. Baltrushis, Data from Papers' Presented at the 18th Republic Scientific-Technical Conference in Kaunas [in Russian], (1968), p. 71.

  8. A. K. Purenas and R. S. Baltrushis, Trudy AN LitSSR, Ser. B., 3(26), 203 (1961).

    Google Scholar 

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 524–526, April, 1971.

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Baltrushis, R.S., Beresnevichyus, Z.I.G. & Zubene, A.I. Synthesis of 1-(4-bromo-1-naphthyl)-dihydrouracil and some of its transformations. Chem Heterocycl Compd 7, 488–490 (1971). https://doi.org/10.1007/BF00471491

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  • DOI: https://doi.org/10.1007/BF00471491

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