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Chemistry of Heterocyclic Compounds

, Volume 11, Issue 2, pp 226–229 | Cite as

Mass-spectrometric study of the structures of the metabolites of bis(1-aziridinyl)-2-pyrimidylaminophosphine oxide (phosphemide)

  • L. F. Linberg
  • Yu. N. Sheinker
  • T. S. Safonova
Article
  • 23 Downloads

Abstract

The principal pathways of fragmentation of bis(1-aziridinyl)-2-pyrimidylaminophosphine oxide and its metabolites under the influence of electron impact that are characteristic for this group of compounds were established. Bis(2-chloroethylamino)-2-pyrimidylaminophosphine oxide and 1-aziridinyl-2-chloroethylamino-2-pyrimidylaminophosphine oxide structures were assigned to the isolated metabolites.

Keywords

Oxide Organic Chemistry Electron Impact Oxide Structure Principal Pathway 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

  1. 1.
    Zh. F. Presnova, T. S. Safonova, V. A. Chernov, and T. F. Vlasova, Farmakol. i ToksikoL, 1 (1974).Google Scholar
  2. 2.
    L. F. Linberg, V. P. Pakhomov, N. S. Kurytov, G. F. Presnova, V. A. Chernov, and T. S. Safonova, Fourth International Symposium on Advances and Utilization of Chromatography, Bratislava (1973).Google Scholar

Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • L. F. Linberg
    • 1
  • Yu. N. Sheinker
    • 1
  • T. S. Safonova
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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