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Chemistry of heteroanalogs of isoflavones

I. Synthesis of furan and benzofuran analogs of isoflavones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

3-Hetaryl-7-methoxychromones were obtained by reaction of α-(5-ethoxycarbonyl-2-furyl)-, α-(2-benzofuryl)-, and α-(2-methoxy-carbonyl-5-benzofuryl)-2-hydroxy-4-methoxyacetophenones with methyl formate or ethyl orthoformate, and 3-hetaryl-4-hydroxy-7-methoxy-coumarins were obtained by reaction of the same compounds with diethyl carbonate. Methods for the synthesis of 3-hetaryl-7-hydroxy-chromones from α-furyl- and α-benzofuryl-substituted, 2,4-dihydroxyacetophenones were investigated.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 174–179, February, 1975.

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Szabo, V., Grishko, L.G., Borbei, S. et al. Chemistry of heteroanalogs of isoflavones. Chem Heterocycl Compd 11, 147–151 (1975). https://doi.org/10.1007/BF00471385

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  • DOI: https://doi.org/10.1007/BF00471385

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