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Hydroxylamine derivatives

III. Synthesis and some reactions of hydroxylamine derivatives of 2-methylbenzimidazole

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The condensation of urethane and ethyl acetohydroximate with 2-chloromethyl-1-methylbenzimidazole has given, respectively, N-ethoxycarbonyl-O-(1-methylbenzimidazol-2-ylmethyl)hydroxylamine and ethyl N-(1-methylbenzimidazol-2-ylmethoxy)acetimidate. Acid hydrolysis of the latter has given O-(1-methylbenzimidazol-2-ylmethyl)hydroxylamine. The reactions of its derivatives with HCl have been studied, and it has been shown that 1-methylbenzimidazole-2-aldehyde O-(1-methylbenzimidazole-2-methyl)oxime is formed. The structure of the latter has been shown by an analysis of its PMR spectra.

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References

  1. Yu. V. Markova, N. G. Ostroumova, and M. N. Shchukina, ZhOrKh, 3, 1207, 1967.

    Google Scholar 

  2. E. L. Schumann, R. V. Heinzelman, M. E. Greig, and W. Veldkamp, J. Med. Chem., 7, 329, 1964.

    Google Scholar 

  3. B. Y. R. Nicolaus, G. Pagani, and E. Testa, Helv. Chim. Acta, 45, 1381, 1962.

    Google Scholar 

  4. L. W. Jones and R. T. Major, J. Am. Chem. Soc., 52, 669, 1930.

    Google Scholar 

  5. H. S. Hensel, Ber., 98, 1329, 1965.

    Google Scholar 

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Authors and Affiliations

  1. Ordzhonikidze All-Union Scientific-Research Chemical and Pharmaceutical Institute, Moscow

    Yu. V. Markova, N. G. Ostroumova, V. I. Lebedeva & M. N. Shchukina

Authors
  1. Yu. V. Markova
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  2. N. G. Ostroumova
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  3. V. I. Lebedeva
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  4. M. N. Shchukina
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For part II, see ¦1¦.

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Markova, Y.V., Ostroumova, N.G., Lebedeva, V.I. et al. Hydroxylamine derivatives. Chem Heterocycl Compd 6, 385–388 (1970). https://doi.org/10.1007/BF00471249

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  • DOI: https://doi.org/10.1007/BF00471249

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