Abstract
The reaction of stereoisomers of 2, 5-dialkoxy-3, 4-epoxytetrahydrofuran with secondary amines has given stereoisomers of 2, 5-dialkoxy-4-dialkylamino-3-hydroxytetrahydrofuran. Their configuration have been confirmed by IR spectroscopy.
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References
L. N. Kralinina, R. I. Kruglikova, V. V. Yastrebov, G. P. Krutetskaya, G. I. Samokhvalov, and A. I. Chernyshev, KhGS [Chemistry of Heterocyclie Compounds], collection 2, 1970 (in the press).
E. Eliel, W. Allinger, S. Angyal, and J. Morrison, Conformational Analysis, New York, 200, 1965.
A. Stoll, E. Gucker, and R. Suess, German patent no. 951570, 1956; C. A., 53, 16150, 1959.
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Kralinina, L.N., Kruglikova, R.I. & Bogomolova, V.I. Preparation of stereoisomeric amino alcohols of the furan series. Chem Heterocycl Compd 6, 280–281 (1970). https://doi.org/10.1007/BF00471219
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DOI: https://doi.org/10.1007/BF00471219