Chemistry of Heterocyclic Compounds

, Volume 5, Issue 3, pp 398–399 | Cite as

Intramolecular rearrangements

III. The rearrangement of S-aminoalkyl derivatives of 2-mercaptopyrimidine and 2-mercapto-4,6-diaminopyrimidine
  • L. V. Pavlova
  • F. Yu. Rachinskii
Article
  • 40 Downloads

Abstract

It has been shown that S-β-aminoalkyl derivatives of 2-mercaptopyrimidine and 2-mercapto-4, 6-diaminopyrimidine, containing primary and secondary amino groups, undergo S → N rearrangement in neutral or weakly alkaline solution, with the formation of the corresponding aminothiols. In the case of derivatives of 2-mercapto-4, 6-diaminopyrimidine, however, the S → N rearrangement proceeds more slowly, apparently as a result of the difficulty of formation of the intermediate cyclic compound.

Keywords

Organic Chemistry Alkaline Solution Weakly Alkaline Cyclic Compound Secondary Amino 

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Copyright information

© Consultants Bureau 1972

Authors and Affiliations

  • L. V. Pavlova
    • 1
  • F. Yu. Rachinskii
    • 1
  1. 1.Kirov Academy of Military MedicineLeningrad

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