Skip to main content

Ultrastructural characteristics of mesenchyme in the middle ear

Archives of oto-rhino-laryngology volume 243, pages 162–166 (1986)Cite this article

Summary

Prior to pneumatization of the middle ear, the mesenchyme present undergoes marked changes until it is transformed via a precollagenous step into the tunica propria of the mucosa. The ultrastructural characteristics of the middle ear mesenchyme in the rat reinforce previous light microscopic studies on human temporal bones. The possible interaction between middle ear mesenchyme and its epithelium in pneumatization and in the etiology of cholesteatoma is discussed.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

References

  1. Albrecht W (1950) Die Bedeutung des lockeren Bindegewebes für die Entstehung des Cholesteatoms. Arch Ohren-Nasen-Kehlkopfheilkd 157:341–351

    Google Scholar 

  2. Bast T, Anson BJ (1949) The temporal bone and the ear. Thomas, Springfield, Illinois, p 306

    Google Scholar 

  3. Buch NH, Balslev-Joergensen M (1964) Embryonic connective tissue in the tympanic cavity of the fetus and the newborn. Acta Otolaryngol (Stockh) 58:111–126

    Google Scholar 

  4. Cole RA, Tinling SP (1985) Basal lamina breaks in the histogenesis of cholesteatoma. Laryngoscope 95:270–275

    Google Scholar 

  5. Diamant H (1982) Questions regarding the invasive and invagination theories. In: Sadé J (ed) Cholesteatoma and mastoid surgery. Kugler, Amsterdam, p 297

    Google Scholar 

  6. Eckert-Möbius A (1926) Mikroskopische Untersuchungstechnik und Histologie des Gehörorgans. In: Denker A, Kahler O (eds) Handbuch der Hals-Nasen-Ohrenheilkunde, vol 611. Springer, Berlin, p 211

    Google Scholar 

  7. Guggenheim P (1971) Mesenchyme in the middle ear. Laryngoscope 81:1665–1670

    Google Scholar 

  8. Ito S, Winchester RJ (1963) The fine structure of the gastric mucosa in the rat. J Cell Biol 16:541–543

    Google Scholar 

  9. Lange W (1925) Über die Entstehung der Mittelohrcholesteatome. Z Hals-Nasen-Ohrenheilkd 11:250–271

    Google Scholar 

  10. Luft JM (1961) Improvements in epoxy resin embedding methods. J Biochem Biophys Cytol 9:409–410

    Google Scholar 

  11. Marx H (1947) Handbuch der Ohrenheilkunde. Fischer, Jena, p 282

    Google Scholar 

  12. Proctor B (1964) The development of the middle ear spaces and their surgical significance. J Laryngol 78:631–647

    Google Scholar 

  13. Rauchfuss A (1985) Die myxomatösen Reste im menschlichen Mittelohr. Histologische Untersuchungen ihrer Rückbildung und Mikrophotographie. Laryngol Rhinol Otol 64:441–445

    Google Scholar 

  14. Rauchfuss A, Rauchfuss S (1985) Die Pathohistogenese des primären Cholesteatoms. Arch Otorhinolaryngol [Suppl II]:156–158

    Google Scholar 

  15. Schwarz M (1931) Das individuelle Verhalten der Schleimhautpropria im Mittelohr in ihrer Entwicklung und ihrem Gewebsaufbau. Z Hals-Nasen-Ohrenheilkd 289:98–114

    Google Scholar 

  16. Schwarz M (1966) Das Cholesteatom im Gehörgang und im Mittelohr. Thieme, Stuttgart, p 40

    Google Scholar 

  17. Wittmaack K (1918) Die Otosklerose. Fischer, Jena, p 32

    Google Scholar 

  18. Wittmaack K (1930) Cholesteatombildung, Pneumatisation und Pneumatisationslehre. Arch Ohren-Nasen-Kehlkopfheilkd 125:218–234

    Google Scholar 

Download references

Author information

Affiliations

  1. University ENT Department, Martinistraße 52, D-2000, Hamburg 20, Germany

    A. Rauchfuss

Authors
  1. A. Rauchfuss
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Rauchfuss, A. Ultrastructural characteristics of mesenchyme in the middle ear. Arch Otorhinolaryngol 243, 162–166 (1986). https://doi.org/10.1007/BF00470612

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00470612

Key words

  • Middle ear development
  • Mesenchyme
  • Cholesteatoma
  • Pneumatization