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Research in the imidazole series

LXXXV. Synthesis of thiazolo[2, 3-f]xanthine derivatives from 8-bromotheophylline

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

2-Alkyl(aryl, hetaryl)-6,8-dimethylthiazolo[2,3-f]xanthines were synthesized from 8-bromotheophylline and α-halo ketones with subsequent replacement of the bromine atom by sulfur and cyclization of the resulting 7-acylmethyl-8-thiotheophyllines under the influence of dehydrating agents.

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Literature cited

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Authors and Affiliations

  1. Zaporozhe Medical Institute, All-Union Scientific-Research Institute of the Technology of Blood Substitutes and Hormonal Preparations, Moscow

    A. N. Krasovskii, M. I. Yurchenko, P. M. Kochergin & I. I. Soroka

Authors
  1. A. N. Krasovskii
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  2. M. I. Yurchenko
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  3. P. M. Kochergin
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  4. I. I. Soroka
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Additional information

See [1] for communication LXXXIV.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1121–1123, August, 1975.

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Krasovskii, A.N., Yurchenko, M.I., Kochergin, P.M. et al. Research in the imidazole series. Chem Heterocycl Compd 11, 979–981 (1975). https://doi.org/10.1007/BF00470504

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  • DOI: https://doi.org/10.1007/BF00470504

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