Abstract
The dissociation constants of 1-oxo-4-hydroxypyridazino[4,5-b]quinoxaline were measured by potentiometric titration. It is shown that this compound is a dibasic acid. Its reaction with organic bases, acids, alkalis, and oxidizing agents was studied. Its aminomethylation, hydroxymethylation, and cyanoethylation were also investigated.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature cited
T. G. Koksharova, V. N. Konyukhov, Z. V. Pushareva, and T. A. Pryakhina, Khim. Geterotsikl. Soedin., No. 2, 274 (1972).
J. P. Dailey, D. A. S. I 092,022 (1960); Chem. Zentralblatt, 10,295 (1961).
S. L. Mukherjee, Z. F. Chmielewicz, and T. J. Bardos, J. Pharm. Sci., 57, No. 3, 516 (1968).
T. G. Koksharova, V. N. Konyukhov, G. N. Smotrina, and Z. V. Pushkareva, Khim. Geterotsikl. Soedin., No. 10, 1418 (1973).
T. G. Koksharova, L. F. Lipatova, V. N. Konyukhov, G. N. Smotrina, and Z. V. Pushkareva, Khim. Geterotsikl. Soedin., No. 4, 556 (1973).
E. Domagalina, J., Kurpiel, and N. Koktysz, Roczn. Chem., 43, No. 4, 775 (1969).
Ichiro Yoshioka and Hirotaka Otomasu, Pharm. Bull. (Tokyo), No. 5, 277 (1957).
K. Maurer and B. Boeltger, Ber., 8, 1383 (1938).
B. C. Platt, Nature, 157, 439 (1946).
Author information
Authors and Affiliations
Additional information
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 402–406, March, 1977.
Rights and permissions
About this article
Cite this article
Koksharova, T.G., Konyukhov, V.N., Pushkareva, Z.V. et al. Some properties of 1-oxo-4-hydroxypyridazino[4,5-b]quinoxaline. Chem Heterocycl Compd 13, 326–329 (1977). https://doi.org/10.1007/BF00470321
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00470321