Chemistry of Heterocyclic Compounds

, Volume 5, Issue 4, pp 563–564 | Cite as

The question of the oxidation of α-hydroxypyridine and nicotinic acid by Fenton's reagent

  • L. G. Shevchuk
  • T. A. Boyarskaya
  • N. A. Vysotskaya
Brief Communications

Abstract

The oxidation of nicotinic acid and α-hydroxypyridine by Fenton's reagent (H2O2 + Fe++) takes place with the decomposition of the pyridine ring to form oxalic acid. In this process, half the label from the α-hydroxypyridine passes into one of the oxygen atoms of the oxalic acid and the other oxygen atoms are derived from the hydrogen peroxide. The oxalic acid isolated from the oxidation of the nicotinic acid contains oxygen from the oxidizing agent. The results obtained show that the hydroxylation of the pyridine ring, apparently preceding its decomposition, takes place with the addition of an OH group containing oxygen from the oxidizing agent to the nucleus.

Keywords

Oxidation Oxygen Hydrogen H2O2 Hydrogen Peroxide 

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Copyright information

© Consultants Bureau 1972

Authors and Affiliations

  • L. G. Shevchuk
    • 1
  • T. A. Boyarskaya
    • 1
  • N. A. Vysotskaya
    • 1
  1. 1.Pisarzhevskii Institute of Physical Chemistry AS UkrSSRUSSR

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