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Alkylation of furan, thiophene, and pyrrole with furfuryl alcohol in the presence of the strongly acidic Amberlyst 15 sulfo cation-exchange resin

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The corresponding 2-furylhetarylmethanes were obtained by the reaction of furan, thiophene, or pyrrole with furfuryl alcohol in the presence of the strongly acidic Amberlyst 15 cation-exchange resin in the H+ form. The alkylation of furan and thiophene takes place regiospecifically in the 2 position, whereas 2-furyl-2-pyrrolyl- and 2-furyl-3-pyrrolylmethane in a ratio of 6.2∶1 are formed in the case of pyrrole.

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Authors and Affiliations

  1. Institute of Organic Synthesis, Academy of Sciences of the Latvian SSR, 226006, Riga

    I. G. Iovel', Yu. Sh. Gol'dberg & M. V. Shimanskaya

Authors
  1. I. G. Iovel'
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  2. Yu. Sh. Gol'dberg
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  3. M. V. Shimanskaya
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 746–749, June, 1989.

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Iovel', I.G., Gol'dberg, Y.S. & Shimanskaya, M.V. Alkylation of furan, thiophene, and pyrrole with furfuryl alcohol in the presence of the strongly acidic Amberlyst 15 sulfo cation-exchange resin. Chem Heterocycl Compd 25, 613–616 (1989). https://doi.org/10.1007/BF00470016

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  • DOI: https://doi.org/10.1007/BF00470016

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