Abstract
Depending on the reaction conditions, reaction of 1-methyl-2-formylbenzimidazole with hydantoin gives an aldol or crotonoid condensation product. Alkaline hydrolysis of these products gives 1, 2-dimethylbenzimidazole. The dihydro derivative of the crotonoid condensation product can be hydrolyzed to α-amino-β-(1-methyl-2-benzimidazolyl)-propionic acid.
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Dalgatov, D.D., Simonov, A.M. Synthesis of α-amino-β-(1-methyl-2-benzimidazolyl)propionic acid. Chem Heterocycl Compd 3, 716–717 (1967). https://doi.org/10.1007/BF00468356
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DOI: https://doi.org/10.1007/BF00468356