Archives of oto-rhino-laryngology

, Volume 227, Issue 3–4, pp 624–627 | Cite as

Zur Verträglichkeit bioinerter Aluminiumoxidkeramik im Mittelohr

  • K. Jahnke
  • M. Galic
II. Teil: Sitzungsbericht Tag der Praxis Freie Vorträge

The biocompatibility of aluminium oxide implants in middle ear surgery

Summary

Scanning and transmission electronmicroscopic investigations were performed in order to study the biocompatibility of Al2O3-ceramic in the middle ear of 24 rabbits. Already after 3 weeks the implant was covered with a normal delicate mucous membrane. In electron scanning one could find a cuboidal epithelium, occasionally some ciliated cells. In our transmissionelectronmicroscopic studies the epithelial cells of the mucosa presented a normal appearance, with an intact basement membrane. We observed active fibroblasts but neither a thick fibrous layer nor giants cells. Thus signs of incompatibility could not be detected in any of the cases (up to 10 months). The subepithelial layer exhibits many normal blood vessels and some nerve fibres.

Up to now we implanted more than 150 prostheses of this bioinert material in tympanoplasties. The decisive factors speaking for the usage in middle ear surgery are: (a) optimal biocompatibility, (b) an insured and certain position, (c) after extensive shaping or after a new infection no partial resorption or atrophy of the material, (d) no fixation with the surrounding bone, (e) sufficient rigidity, but a ligament-like connection with the rest of the chain. Our preliminary results are very encouraging as far as compatibility and functional results are concerned.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. 1.
    Heimke G, Griss P, Jentschura G, Krempien B, Gugel E, Petzenhauser I, Hennicke HW (1977) Keramische und keramikbeschichtete Knochenersatzwerkstoffe. BM für Forschung und Technologie, T 77-70Google Scholar
  2. 2.
    Jahnke K, Galic M, Eitel W, Heumann H (1980) Electronmicroscopic observations on. Al2O3-ceramic implants in middle ear surgery. First World Congress on Biomaterials, Wien 1980Google Scholar
  3. 3.
    Galic M, Jahnke K (1980) Histological studies on plastic middle ear prostheses. (In preparation)Google Scholar
  4. 4.
    Jahnke K, Plester D (1980) Praktische Hinweise zur Anwendung von Mittelohr-Implantaten aus Aluminiumoxid-Keramik. HNO 28: 115–118Google Scholar

Copyright information

© Springer-Verlag 1980

Authors and Affiliations

  • K. Jahnke
    • 1
  • M. Galic
    • 1
  1. 1.Tübingen

Personalised recommendations