Summary
The turnover time of the epithelial cells of a normal eustachian tube was estimated in guinea pigs by means of lightmicroscopic autoradiography with thymidine-H3.
The cell migration from the basal layer to the tubal lumen was chased by sacrificing the animals at different intervals after thymidine-H administration. This study revealed that the generative cells were the basal cells in the tubal epithelium and that the different types of maturative cells in the epithelium have a different life span. The turnover time of non-ciliated secretory cells was about 145 hrs (about 6 days), while that of ciliated cells and goblet cells more than 6 days.
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Watanuki, K., Tanaka, K. & Kawamoto, K. Cell renewal in the eustachian tube epithelium of guinea pigs. Arch Otorhinolaryngol 211, 65–68 (1975). https://doi.org/10.1007/BF00467292
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DOI: https://doi.org/10.1007/BF00467292