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Twelve years of experience with cytotoxic therapy in malignant tumors of the neck and head

Zwölf Jahre Erfahrung mit zytotoxischer Therapie maligner Tumoren an Kopf und Hals

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Zusammenfassung

Zwischen 1968 und 1981 wurden 164 bösartige Tumoren an Kopf und Hals, 151 davon als unheilbar eingestuft, mit Chemotherapie isoliert oder mit Radiotherapie bzw. Chirurgie kombiniert behandelt. Chemotherapeutische Protokolle, Behandlungsmethode und Ergebnisse werden ausführlich besprochen. In einigen Fällen wurde die Heilung nur mit Zytostatika erreicht. In anderen Fällen ist es uns gelungen, mit Radio- und Chemotherapie ausgedehnte Operationen zu vermeiden.

Summary

Since 1968 we have treated with antiblastic drugs 164 malignant tumors recurrant or incurable by surgery or radiotherapy in 151 cases. Different therapeutic methods were employed. Today we have the possibility of selecting alternative options with incipient or relatively delimited carcinomas, principally the substitution of radical surgery by initial associated physical and chemical treatment, so that if there is a cure the consequences of radical surgery can be avoided. We emphasize the cure of two primary cancers of the uvula with 300 mg bleomycin exclusively and the results observed in oropharyngeal and laryngeal carcinomas by using three intermittent Schabel cycles and 4,000 rad Telecobalt, avoiding a radical surgery.

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Bartual, J., Roquette, J., Gil, M. et al. Twelve years of experience with cytotoxic therapy in malignant tumors of the neck and head. Arch Otorhinolaryngol 234, 305–312 (1982). https://doi.org/10.1007/BF00464335

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  • DOI: https://doi.org/10.1007/BF00464335

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