Summary
In order to be able to describe the systemic cellular immunity in patients with ozena, the following immunologic parameters were studied in 19 ozena patients: the number of T-and B-cells, the spontaneously proliferating cells, and the transformation response of lymphocytes to phytohemagglutinin and pokeweed mitogen. No differences could be found between the ozena patients and the healthy control subjects, however. Subsequently, with the methods used, we were unable to find any systemic cellular immuno-disorders in patients with ozena.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Bernat I (1965) Ozaena. A manifestation of iron deficiency, 1st edn. Pergamon Press, Oxford, United Kingdom
Crowther D, Fairley GH, Sewell RL (1969) Lymphoid cellular responses in the blood after immunization in man. J Exp Med 129: 849–862
Fouad H, Afifi N, Fatt-Hi A, El-Sheemy N, Iskander I, Abon Saif MN (1980) Altered cell mediated immunity in atrophic rhinitis. J Laryngol Otol 94: 507–514
Goodman JW, Wang A-C (1978) Immunoglobulins: structure and diversity. Basic and clinical immunology, 2nd edn. Lange Medical Publications, California, pp 23–38
Holopainen E (1967) Nasal mucous membrane in atrophic rhinitis with reference to symptom free nasal mucosa. Histology, histo-chemistry and exfoliative cytology. Acta Otolaryngol Suppl 227
Lalla M, Vesikari T, Virolainen M (1973) Lymphoblast proliferation and humoral antibody response after ruebella vaccination. Clin Exp Immunol 15: 193–202
Marchalonis JJ (1978) Cell cooperation in immune responses. Basic and clinical immunology, 2nd edn. Lange Medical Publications, California, pp 110–122
Mygind N, Thomsen J, Jørgensen MB (1974) Ultrastructure of the epithelium in atrophic rhinitis. Transmission electron microscopic studies. Acta Otolaryngol 78: 106–112
Schmidt G (1968) Die Serumeiweißkörper bei der Ozaena. Montasschr Ohrenheilkd Laryngorhinol 102: 223–229
Sipilä P, Ryhänen P, Karma P (1979) T cells as marked with acid α-naphthyl acetate esterase staining in secretory otitis media. Acta Otolaryngol (Stockh) Suppl 360: 216–220
Surjan L, Surjan M (1962) Serobakteriologische Untersuchungen bei Rhinitis atrophicans foetida. Aetologie der Ozaena. Z Laryngol 41: 70–76
Weksler and Kuntz (1976) Synergy between human T-and B-lymphocytes in their response to phytohaemagglutinin and pokeweed mitogen. Immunology 31: 273–279
Zippel R, Werner E (1967) Histopathologische und serologische Befunde bei Ozaena. Z Laryngol Rhinol Otol 46: 289–297
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sipilä, P., Hyrynkangas, K. Immunologic aspects of ozena. Arch Otorhinolaryngol 239, 249–253 (1984). https://doi.org/10.1007/BF00464251
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00464251