Summary
Pseudomonas aeruginosa, proteus mirabilis, citrobacter intermedius, staphylococcus aureus haemolyticus and staphylococcus albus produce extracellular proteinases with maximum activity at pH 7.8. These proteinases are inhibited practically completely by human and animal blood serum. This inhibitory activity of human serum is caused by alpha-2-macroglobulin. Ovomucoid showed nearly the same inhibitory activity as alpha-2-macroglobulin.
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Theopold, HM., Hochstraßer, K. & Bauernfeind, A. Untersuchung verschiedener Bakterienproteinasen und ihre Hemmbarkeit durch natürliche Proteinaseninhibitoren. Arch Otorhinolaryngol 207, 472–473 (1974). https://doi.org/10.1007/BF00464133
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DOI: https://doi.org/10.1007/BF00464133