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The barrier-like role of activated connective tissue against the spread of supraglottic laryngeal carcinoma

Archives of oto-rhino-laryngology volume 245, pages 151–154 (1988)Cite this article

Summary

Light microscopic investigations of whole organ serial sections of 15 laryngectomy specimens with supraglottic carcinomas and comparative electron microscopic studies of the upper and lower poles of the tumors were carried out. The ultrastructure of different poles of the same supraglottic tumors was investigated and showed a more progressive fibrillogenesis with an activation of the connective tissue elements of the border on the lower pole of the malignancy. A significant role is attributed to the barrierforming feature of activated connective tissue with respect to the inhibition of the extension of tumor into the glottic region.

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Author information

Affiliations

  1. Department of Oto-Rhino-Laryngology, Semmelweis University, Szigony u. 36, H-1083, Budapest, Hungary

    G. Répássy & O. Ribári

  2. Department of Oto-Rhino-Laryngology, University of Szeged, Hungary

    J. Czigner

  3. First Institute of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary

    K. Lapis

Authors
  1. G. Répássy
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  2. J. Czigner
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  3. O. Ribári
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  4. K. Lapis
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Répássy, G., Czigner, J., Ribári, O. et al. The barrier-like role of activated connective tissue against the spread of supraglottic laryngeal carcinoma. Arch Otorhinolaryngol 245, 151–154 (1988). https://doi.org/10.1007/BF00464017

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  • DOI: https://doi.org/10.1007/BF00464017

Key words

  • Supraglottic carcinoma
  • Light microscopy
  • Electron microscopy
  • Activated connective tissue barrier