Summary
Intestinal absorption of glyoeryl tri-[1-14C]-oleate and [1-14C]-oleic acid, measured by serial determinations of blood radioactivity after oral administration of the compounds in peanut oil, was significantly greater in non-ketotic diabetic Chinese hamsters than in nondiabetic controls. Incorporation of [1-14C]-oleic acid into tissue lipids by jejunal slices in vitro was equal in both groups on a unit tissue weight basis. The data suggest that intraluminal hydrolysis does not differ between diabetic and non-diabetic animals. Overall uptake of free fatty acids may be enhanced in diabetics as a consequence of increased small intestinal mass.
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Parkinson, T.M. Enhanced intestinal fat absorption in diabetic chinese hamsters. Diabetologia 9, 505–508 (1973). https://doi.org/10.1007/BF00461697
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DOI: https://doi.org/10.1007/BF00461697