Ultrastruktur der Epidermolysis bullosa acquisita

Summary

Epidermolysis bullosa acquisita is a rarely occurring disorder which in contrast to the other types of epidermolysis bullosa is not hereditary. Epidermolysis bullosa acquisita is further distinguished by the following criteria: clinical lesions of epidermolysis bullosa dystrophica, onset of disease in adulthood, exclusion of other bullous diseases, and ultrastructural as well as immunopathological alterations. Skin lesions and for the first time lesions situated on the mucous membranes of the upper respiratory tract and esophagus were studied by light and electron microscopy and with immunofluorescence and immunoelectron microscopic methods. The results are discussed in terms of current immunological findings.