Advertisement

Archives of oto-rhino-laryngology

, Volume 235, Issue 2–3, pp 429–430 | Cite as

Reaktionen von Tonsillen- und Blutlymphocyten gegenüber Streptokokken-Antigenen bei chronischer Tonsillitis im Transformationstest

  • H. Enzmann
  • R. Steinriede
  • K. Klugius
II. Teil: Sitzungsbericht Varia

In vitro stimulation of human tonsillar and blood lymphocytes with streptococcal antigens in chronic tonsillitis

Summary

Stimulations of tonsillar and blood lymphocytes with many streptococcal extracellular antigens and streptococcal membrane antigen in patients suffering from chronic tonsillitis were done. The in vitro cellular immunresponse depends on the antigen, the age of the patient and the origin of the lymphocytes: blood or tonsil. There is good evidence, that there is a selective unresponsiveness of the blood lymphocytes of adult patients, stimulated with streptococcal membrane antigen.

Literatur

  1. Banck G, Forsgren A (1978) Many bacterial species are mitogenic for human blood B lymphocytes. Scand J Immunol 8: 347Google Scholar
  2. Bültmann B, Sachsenmayer W, Heymer B, Haverkamp O (1970) Untersuchungen zur zellgebundenen Überempfindlichkeit gegen Streptokokkenzellwandantigene. Verh Dtsch Ges Pathol 54: 329Google Scholar
  3. Francis TC, Oppenheim JJ (1970) Impaired lymphoid stimulation by some streptococcal antigens in patients with recurrent aphtous stomatitis and rheumatic heart disease. Clin Exp Immunol 6: 573Google Scholar
  4. Hurdato RC, Rola-Pleszcynski M, Mend MA (1975) The immunologic role of tonsillar tissues in local cell-mediated immune responses. J Pediatr 86: 405Google Scholar
  5. McLaughlin JF, Paterson PY, Hartz RS, Embury SH (1972) Rheumatic carditis. In vitro responses of peripheral blood leukocytes to heart and streptococcal antigens. Arthritis Rheum 15: 600Google Scholar
  6. Mihalcu F, Gerlesanu M (1976) In-vitro lymphocyte response to streptococcal antigens in rheumatic fever cases. Arch Roum Pathol Exp Microbiol 35/1–2: 133Google Scholar
  7. Rynnel-Dagöö B, Ringden O, Alfredson H, Möller E (1978) The use of bacteria for the functional characterization of human lymphocyte subpopulations in various lymphoid organs. Scand J Immunol 8: 369Google Scholar
  8. Siegel GJ, Wilke J (1975) Die Biosynthese von Nukleinsäuren und Proteinen in isolierten menschlichen Tonsillenzellen in Abhängigkeit vom Lebensalter. Arch Otolaryngol 209: 113Google Scholar
  9. Zabriskie JB, Lewshenia R, Möller G, Wehle B, Falk RE (1970) Lymphocytic response to streptococcal antigens in glomerulonephritic patients. Science 168: 1105Google Scholar

Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • H. Enzmann
    • 1
  • R. Steinriede
    • 1
  • K. Klugius
    • 1
  1. 1.Heidelberg

Personalised recommendations