Summary
Stimulations of tonsillar and blood lymphocytes with many streptococcal extracellular antigens and streptococcal membrane antigen in patients suffering from chronic tonsillitis were done. The in vitro cellular immunresponse depends on the antigen, the age of the patient and the origin of the lymphocytes: blood or tonsil. There is good evidence, that there is a selective unresponsiveness of the blood lymphocytes of adult patients, stimulated with streptococcal membrane antigen.
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Enzmann, H., Steinriede, R. & Klugius, K. Reaktionen von Tonsillen- und Blutlymphocyten gegenüber Streptokokken-Antigenen bei chronischer Tonsillitis im Transformationstest. Arch Otorhinolaryngol 235, 429–430 (1982). https://doi.org/10.1007/BF00459872
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DOI: https://doi.org/10.1007/BF00459872