Feinstrukturelle Befunde am Cortischen Organ nach experimenteller Beschallung mit Sinustönen

Summary

28 guinea pigs were exposed to the pure tone stimulus of 3000 Hz with different intensity of 85–130 dB SPL (15 min, 130 dB up to 126 h, 85 dB SPL). The inner ears were examined by means of scanning and transmission electron microscopy. The location of hair cell lesions were found accordingly to the frequency at the end of the basal coil to the 1st coil from base. The complete loss of all cell structures was observed either after a long term stimulation of low intensity or after short time sound exposure of high intensity (15 min, 130 dB). The fine structural alterations of the same specimen could be examined by means of scanning and of transmission electron microscopy due to a special embedding procedure.

The tonotopical damage of the organ of Corti after pure tone stimulation suggest a mainly mechanical overstimulation of these areas.