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Seltene Lokalisation extramedullärer Plasmocytome

Unusual location of extramedullary plasmacytomas

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Summary

Two cases of solitary extramedullary plasmacytoma, one of the nasopharynx and one of the tongue are reported. Although there was no paraprotein secretion present, we were able to demonstrate an intracytoplasmic monoclonal immunoglobulin (type IgG-kappa) by immunohistochemical methods. Twelve months following surgical treatment both patients locally and by serum controls are free of residual disease. We confirm former studies in the literature that the prognosis of solitary extramedullary plasmacytomas seems to be good after surgical or radiation therapy. Continuous individual follow-up including serum and X-ray controls are obligatory.

Zusammenfassung

Zwei Beobachtungen eines solitären extramedullären Plasmocytoms des Epipharynx bzw. der Zunge werden vorgestellt, bei denen trotz fehlender Paraproteinsekretion intracytoplasmatisch ein monoklonales Immunglobulin vom Typ Ig G, Kappa, immunhistochemisch nachgewiesen werden konnte. Nach chirurgischer Exstirpation im Gesunden sind beide Patienten nach einem Beobachtungszeitraum von 12 bzw. 14 Monaten rezidivfrei. Bei regelmäßiger Kontrolle scheint die Prognose des solitären extramedullären Plasmocytoms nach chirurgischer oder kombinierter chirurgisch-radiologischer Therapie günstig zu sein.

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Authors and Affiliations

  1. Pathologisches Institut der Universität, Moorenstraße 5, D-4000, Düsseldorf, Bundesrepublik Deutschland

    A. Schmitt-Gräff

  2. Hals-Nasen-Ohrenklinik der Universität, Moorenstraße 5, D-4000, Düsseldorf, Bundesrepublik Deutschland

    W. Arnold

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  1. A. Schmitt-Gräff
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  2. W. Arnold
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Schmitt-Gräff, A., Arnold, W. Seltene Lokalisation extramedullärer Plasmocytome. Arch Otorhinolaryngol 225, 257–264 (1979). https://doi.org/10.1007/BF00455677

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  • DOI: https://doi.org/10.1007/BF00455677

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