Skip to main content
Log in

Pseudolymphoma of skin induced by oriental hornet (Vespa orientalis) venom

Ultrastructural study

  • Original Papers
  • Published:
Archives of Dermatological Research Aims and scope Submit manuscript

Summary

A single subcutaneous injection of Oriental hornet venom into black mice led to the development of a subcutaneous nodule which showed no change during the period of 1 year. Study of the ultrastructure revealed an accumulation of lymphocytes and lymphoblasts and a few plasma cells with formation of Russel bodies. In addition, a few melanin-containing macrophages and macrophages filled with cellular debris were found. This reaction is compared to other pseudolymphomatous reactions in the dermis.

Zusammenfassung

Eine einmalige sucutane Injektion des Giftes der orientalischen Wespe führt bei schwarzen Mäusen zu der Entwicklung eines subcutanen Knötchens, welches sich über 1 Jahr hält. Ultrastrukturell zeigt sich eine Anreicherung von Lymphocyten und Lymphoblasten und einige Plasmazellen mit Russelkörperchen. Zusätzlich werden einige Melanin enthaltende Makrophagen und auch solche mit aufgenommenen cellulären Abbauprodukten beobachtet. Die gesamte Reaktion wird mit anderen pseudolymphomatösen Reaktionen in der Haut in Beziehung gesetzt.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Allen, A. C.: Persistent “inset bites” (dermal eosinophilic granulomas) simulating lymphoblastomas, histiocytoses and squamous cell carcinomas. Amer. J. Path. 24, 367–387 (1948)

    Google Scholar 

  • Allen, A. C.: Reactions to arthropodes. In: The skin, 2. ed., pp. 561–568. New York: Grune & Stratton 1967

    Google Scholar 

  • Barr-Nea, L., Rosenberg, P., Ishay, P.: The venom apparatus of Vespa orientalis. Morphology and cytology. Toxicon 14, 65–68 (1976)

    Google Scholar 

  • Barr-Nea, L., Sandbank, M., Ishay, J.: Pseudolymphoma of skin induced by Oriental hornet (Vespa orientalis) venom. Experientia 32, 1564–1565 (1976)

    Google Scholar 

  • Barr-Nea, L., Ishay, J.: Histopathological changes in mouse and rat skin injected with venom sac extracts of the oriental hornet (Vespa orientalis). Toxicon 15, 301–306 (1977)

    Google Scholar 

  • Edery, H., Ishay, J., Lass, Y., Gitter, S.: Pharmacological activity of Oriental hornet (Vespa orientalis) venom. Toxicon 10, 13–19 (1972)

    Google Scholar 

  • Künzig, M., Steigleder, G. K.: Histopathologische Untersuchungen des Mückenstichinfiltrates bei Patienten mit verschiedenen Grunderkrankungen und unterschiedlicher Medikation. Z. Hautkrkh. 52, 37–41 (1977)

    Google Scholar 

  • Mann, G. T., Bates, H. R.: The pathology of insect bites: A brief review and report of eleven fatal cases. Southern Med. J. 53, 1392–1399 (1960)

    Google Scholar 

  • Mori, Y., Lennert, K.: Electron microscopic atlas of lymph node cytology and pathology. Berlin-Heidelberg-New York: Springer Verlag 1969

    Google Scholar 

  • Schmoeckel, C., Burg, G., Wolff, H. H., Braun-Falco, O.: The ultrastructure of lymphadenosis benigna cutis (pseudolymphoma cutis). Arch. Derm. Res. 258, 161–167 (1977)

    Google Scholar 

  • Weir, D. M.: Handbook of experimental immunology. Oxford: Blackwell Scient. Pub. 1967

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sandbank, M., Barr-Nea, L. & Ishay, J. Pseudolymphoma of skin induced by oriental hornet (Vespa orientalis) venom. Arch Dermatol Res 262, 135–141 (1978). https://doi.org/10.1007/BF00455382

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00455382

Key words

Schlüsselwörter

Navigation