Skip to main content
Log in

Further similarities between Sézary syndrome and mycosis fungoides

  • Original Papers
  • Published:
Archives of Dermatological Research Aims and scope Submit manuscript

Summary

Sézary syndrome and mycosis fungoides, both malignant Non-Hodgkin lymphomas, although characterized as specific entities, show a close relationship. This is based on striking similarities not only with respect to morphological, cytophotometrical, cytogenetical and immunological findings, but also with respect to a typical common reaction pattern to photochemotherapy.

Zusammenfassung

Zwischen den beiden als maligne Non-Hodgkin-Tumoren klassifizierbaren, jedoch gut voneinander abzutrennenden Krankheitsbildern Sézary-Syndrom un Mykosis fungoides bestehen enge Beziehungen. Diese beruhen nicht nur auf morphologischen, cytophotometrischen, cytogenetischen und immunologischen Befunden, sondern darüber hinaus läßt sich ein gemeinsames charakteristisches Reaktionsmuster gegenüber photochemotherapeutischen Einwirkungen erkennen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Bickhardt, R., Kunze, J.: Beiträge zur immunologischen Reaktionsbereitschaft beim malignen Melanom. Z. Hautkr. 49, 315–333 (1974)

    Google Scholar 

  • Born, A., Born, W.: Blacklight-Meladinine-Photochemotherapie (PUVA). Akt. Derm. 1, 187–198 (1975)

    Google Scholar 

  • Born, W.: To be published.

  • Bosman, F. T., Vloten, W. A. van: Sézary's syndrome: A cytogenetic, cytophotometric and autoradiographic study. J. Path. 118, 49–57 (1976)

    Google Scholar 

  • Claudy, A. L.: The immunological identification of the Sézary cell. Brit. J. Derm. 91, 597–600 (1974)

    Google Scholar 

  • Crossen, P. E., Mellor, J. E. L., Ravich, R. B. M., Vincent, P. C., Gunz, F. W.: The Sézary syndrome. Cytogenetic studies and identification of the Sézary cell as an abnormal lymphocyte. Amer. J. Med. 50, 24–34 (1971)

    Google Scholar 

  • Ding, J. C., Adams, P. B., Patison, M., Cooper, I. A.: Thymic origin of abnormal lymphoid cells in Sézary syndrome. Cancer 35, 1325–1332 (1975)

    Google Scholar 

  • Hagedorn, M., Kannen, M. von, Petres, J.: Mycosis fungoides-Klinik, Histopathologie und Therapie. Akt. Derm. 2, 209–216 (1976)

    Google Scholar 

  • Hagedorn, M., Schmitt, E., Petres, J., Meuret, G.: Monocyte consuming process in mycosis fungoides and Hodgkin disease. Arch. Derm. Res. 255, 106–107 (1976)

    Google Scholar 

  • Hagedorn, M.: Zur Morphologie und Monozytopoese der Mycosis fungoides. Fortschr. Med. 95, 793–798 (1977)

    Google Scholar 

  • Hagedorn, M., Kiefer, G.: DNA content of mycosis fungoides cells. Arch. Derm. Res. 258, 127–134 (1977)

    Google Scholar 

  • Hagedorn, M., Kiefer, G., Riede, U.: Electron microscopic findings in mycosis fungoides. J. Cutan. Path. 4, 212 (1977)

    Google Scholar 

  • Hofmann, C., Burg, G., Plewig, G., Braun-Falco, O.: Photochemotherapie kutaner Lymphome. Dtsch. Med. Wschr. 102, 675–678 (1977)

    Google Scholar 

  • Korting, G. W., Hoede, N.: “Lymphodermia perniciosa”. Arch. Derm. Res. 245, 211–220 (1972)

    Google Scholar 

  • Löffler, H., Meyhöfer, W., Lange, R. H., Ehlers, G., Remmele, W.: Sézary-Syndrom eine leukämische Variante der Mykosis fungoides. Dtsch. Med. Wschr. 99, 429–434 (1974)

    Google Scholar 

  • Lutzner, M. A., Emerit, I., Durepaire, R., Flandrin, G., Grupper, Ch., Prunieras, M.: Cytogenetic, cytophotometric, and ultrastructural study of large cerebriform cells of the Sézary syndrome and description of a small-cell variant. J. Nat. Cancer Inst. 50, 1145–1162 (1973)

    Google Scholar 

  • Meuret, G.: Monozytopoese beim Menschen. Blut Suppl. 13 (1974)

  • Meuret, G., Schmitt, E., Hagedorn, M.: Monocytopoiesis in chronic eczematous diseases, psoriasis vulgaris and mycosis fungoides. J. invest. Derm. 66, 22–28 (1976)

    Google Scholar 

  • Mackie, R., Sless, F. R., Cochran, R., De Sousa, M.: Lymphocyte abnormalities in mycosis fungoides. Brit. J. Derm. 94, 173–178 (1976)

    Google Scholar 

  • Pfeiffer, R. A.: Cell cultures from blood and bone marrow. In: Methods in human cytogenetics. Eds.: H. G. Schwarzacher, U. Wolf. Berlin-Heidelberg-New York: Springer 1974

    Google Scholar 

  • Seiler, F. R., Sedlacek, H. H., Kanzy, E. J., Lang, W.: Über die Brauchbarkeit immunologischer Nachweismethoden zur Differenzierung funktionell verschiedener Lymphozyten: Spontanrosetten, Komplementrezeptor-Rosetten und Immunglobulinrezeptoren. Behring Inst. Mitteilungen 52, 26–34 (1972)

    Google Scholar 

  • Sézary, A., Bouvrain, Y.: Erythrodermie avec présence de cellules monstrueuses dans le derme et le sang circulant. Bull. Soc. Franc. Derm. Syph. 45, 254–260 (1938)

    Google Scholar 

  • Tan, R. S. H., Butterworth, C. M., McLaughlin, H., Malka, S., Samman, P. D.: Mycosis fungoides—a disease of antigen persistence. Brit. J. Derm. 91, 607–616 (1974)

    Google Scholar 

  • Thomas, C.: Zur Systematik und Pathologie der Lymphome. Therapiewoche 26, 1971–1982 (1976)

    Google Scholar 

  • Winkelmann, R. K.: T cell Erythroderma (Sézary syndrome). Arch. Derm. 108, 205–206 (1973)

    Google Scholar 

  • Winkelmann, R. K., Linman, J. W.: Erythroderma with atypical lymphocytes (Sézary syndrome). Amer. J. Med. 55, 192–198 (1973)

    Google Scholar 

  • Wybran, J., Fudenberg, H.: Thymus-derived rosette forming cells. New Engl. J. Med. 288, 1072–1073 (1973)

    Google Scholar 

  • Wybran, J., Fudenberg, H.: How clinical useful is T and B cell quantitation? Ann. Int. Med. 80, 765–767 (1974)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hagedorn, M., Born, W., Kunze, J. et al. Further similarities between Sézary syndrome and mycosis fungoides. Arch Dermatol Res 261, 253–258 (1978). https://doi.org/10.1007/BF00455293

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00455293

Key words

Schlüsselwörter

Navigation