Motor nerve conduction velocity in asymptomatic lead workers

  • P. -E. Paulev
  • C. Gry
  • M. Døssing


No difference was found between the nerve conduction velocities of the ulnar nerve of 32 lead exposed workers in the mill of a lead-zinc mine, compared to that of a control group of 14 persons. The lead exposure period was 2–37 months (mean: 12.9 months).

The blood lead of the exposed group was as an average (± SD): 53 ± 16 μg per 100 ml compared to 11 ± 4 μg per 100 ml for the control group.

Further studies are needed to establish a possible dose-time-response relationship for the possible, subclinical neuropathy found by some investigators.

Key words

Lead workers Blood lead Nerve conduction 


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  1. Araki, S., Honma, R.: Relationships between lead absorption and peripheral nerve conduction velocities in lead workers. Scand. J. Work Environ. Health 4, 225–231 (1976)Google Scholar
  2. Brangstrup Hansen, P., Døssing, M., Gry, C., Paulev, P.-E.: Urinary lead excretion following a standardized infusion of calcium-disodium-ethylendiaminetetraacetate (in press)Google Scholar
  3. Cantarow, A., Trumper, M.: Lead poisoning, pp. 1–45. Baltimore, MD: Williams and Wilkins 1944Google Scholar
  4. Catton, M. J., Harrison, M. J. G., Fullerton, P. M., Kazantzis, G.: Subclinical neuropathy in lead workers. Br. Med. J. 2, 80–82 (1970)Google Scholar
  5. Hernberg, S.: Biological effects of low lead doses. Int. symp. on environmental aspects of lead. Die gesundheitlichen Aspekte der Umweltverschmutzung durch Blei, eds. D. Barth et al. Commission of the EEC, Luxembourg 1973Google Scholar
  6. Kehoe, R. A.: The harben lectures, pp. 1–11. London: McCorquodale 1960Google Scholar
  7. Lilis, R., Fischbein, A., Diamond, S., Anderson, H. A., Selikoff, I., Blumberg, W., Eisinger, J.: Lead effects among secondary lead smelter workers with blood lead levels below 80 μg/100 ml. Arch. Environ. Health 32, 256–263 (1977)Google Scholar
  8. Ludwig, J. H., Diggs, D. R., Hesselberg, H. E.: Survey of lead in the atmosphere of three urban communities: A summary. Am. Ind. Hyg. Assoc. J. 26, 270–284 (1965)Google Scholar
  9. Paulev, P.-E., Solgaard, P., Tjell, J. C.: Interlaboratory lead and cadmium comparison in blood and liquids. Clin. Chem. 24, 1797–1800 (1978)Google Scholar
  10. Savolainen, H.: “Biochemical mechanisms in neurotoxicity”. Sec. Internat. Course in Industr. Toxicology, 270–280. Inst. of Occup. Health, Helsinki, Finland, August 1977Google Scholar
  11. Seppäläinen, A. M., Tola, S., Hernberg, S., Kock, B.: Subclinical neuropathy at “safe” levels of lead exposure. Arch. Environ. Health 30, 180–183 (1975)Google Scholar
  12. Thomasino, J. A., Zuroweste, E., Brooks, S. M., Petering, H. G., Lerner, S. I., Finelli, V. N.: Lead, zinc and erythrocyte-delta aminolevulinic acid-dehydratase. Relationships in lead toxicity. Arch. Environ. Health 32, 244–249 (1977)Google Scholar
  13. Vasilescu, C.: Motor nerve conduction velocity and electromyogram in chronic lead poisoning. Rv. Roum. Neurol. 10, 221–226 (1973)Google Scholar
  14. Verberk, M. M.: Motor nerve conduction velocity in volunteers ingesting inorganic lead for 49 days. Int. Arch. Occup. Environ. Health 38, 141–143 (1976)Google Scholar
  15. Zielhuis, R. L.: Second Int. Workshop permissible levels for occup. exposure to inorganic lead. Int. Arch. Occup. Environ. Health 39, 59–72 (1977)Google Scholar

Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • P. -E. Paulev
    • 1
  • C. Gry
    • 1
  • M. Døssing
    • 1
  1. 1.Institute of Medical Physiology BUniversity of CopenhagenCopenhagen NDenmark

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