Summary
Of 160 cases of osteosarcoma seen over an 18-year period, 18 were over the age of 40 at the time of presentation. The clinical presentation and histology of these cases is reviewed. Delay in referral and incorrect histological diagnoses were frequent. Only 2 cases were associated with Paget's disease.
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Brooks, S., Starkie, C.M. & Clarke, N.M.P. Osteosarcoma after the fourth decade. Arch. Orth. Traum. Surg. 104, 100–105 (1985). https://doi.org/10.1007/BF00454247
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DOI: https://doi.org/10.1007/BF00454247