Summary
A total of 7 patients (3–21 years old) suffering from an intractable “primary” Lennox-Gastaut syndrome (LGS) were treated with i.v. high doses of polyvalent human immunoglobulins. Of these patients 6 improved following such treatment with a decrease in fits and an improvement in the EEG.
Hypotheses about the contribution of the treatment and immunopathological factors in some cases of idiopathic LGS are discussed.
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van Rijckevorsel-Harmant, K., Delire, M. & Rucquoy-Ponsar, M. Treatment of idiopathic west and lennox-gastaut syndromes by intravenous administration of human polyvalent immunoglobulins. Eur Arch Psychiatr Neurol Sci 236, 119–122 (1986). https://doi.org/10.1007/BF00454021
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DOI: https://doi.org/10.1007/BF00454021