Skip to main content
SpringerLink
Log in

Immunohistochemical localization of lysozyme in the nasal respiratory mucosa

  • Published:
Archives of oto-rhino-laryngology Aims and scope Submit manuscript

Summary

By use of the indirect immunoperoxidase method, lysozyme was localized in the serous glands and serous parts of mixed mucous-serous glands of the nasal respiratory area. Histochemically, lysozyme was absent from acini containing acid mucosubstances. These findings are in agreement with localizations of lysozyme in glands at other sites.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Bloom W, Fawcett DW (1975) A textbook of histology, 10th edn. Saunders, Philadelphia, p 743

    Google Scholar 

  2. Bowes D, Corrin B (1977) Ultrastructural immunocytochemical localization of lysozyme in human bronchial glands. Thorax 32:163–170

    Google Scholar 

  3. Chipman DM, Sharon N (1969) Mechanism of lysozyme action. Science 165: 454–465

    Google Scholar 

  4. Fleming A (1922) On a remarkable bacteriolytic element found in tissues and secretions. Proc R Soc Lond [Biol] 93: 206–317

    Google Scholar 

  5. Friedmann I, Osborn DA (1982) Pathology of granulomas and neoplasms of the nose and paranasal sinuses. Churchill Livingstone, Edinburgh London Melbourne New York, p 8

    Google Scholar 

  6. Klockars M, Osserman EF (1974) Localization of lysozyme in normal rat tissues by an immunoperoxidase method. J Histochem Cytochem 22: 139–146

    Google Scholar 

  7. Klockars M, Reitamo S (1975) Tissue distribution of lysozyme in man. J Histochem Cytochem 23: 932–940

    Google Scholar 

  8. McClelland DBL, Furth R van (1975) In vitro synthesis of lysozyme by human and mouse leucocytes and tissues. Immunology 28: 1099–1114

    Google Scholar 

  9. Ogawa H, Kami K, Suzuki, R, Mitsui T (1979) An immunohistochemical study of lysozyme in the human nasal mucosa. Keio J Med 28: 73–79

    Google Scholar 

  10. Spicer SS, Frayser R, Virella G, Hall BJ (1977) Immunocytochemical localization of lysozyme in respiratory and other tissues. Lab Invest 36: 282–295

    Google Scholar 

  11. Sternberger LA, Hardy PH Jr, Cuculis JJ, Meyer HG (1970) The unlabeled antibody-enzyme method of immunohistochemistry. Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes. J Histochem Cytochem 18: 315–333

    Google Scholar 

  12. Taylor M (1958) Histochemistry of the nasal respiratory mucosa. J Laryngol 72: 365–376

    Google Scholar 

  13. Terrahe K (1973) Immunpathologische Aspekte bei der chronisch-hyperplastischen Rhinosinusitis. HNO 21: 145–152

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, Laboratorium voor Histochemie en Cytochemie, A. Z. St. Rafaël, Katholieke Universiteit Leuven, Minderbroedersstraat 12, B-3000, Leuven, Belgium

    J. J. van den Oord, C. De Wolf-Peeters & V. Desmet

Authors
  1. J. J. van den Oord
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. De Wolf-Peeters
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. Desmet
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

van den Oord, J.J., De Wolf-Peeters, C. & Desmet, V. Immunohistochemical localization of lysozyme in the nasal respiratory mucosa. Arch Otorhinolaryngol 237, 1–5 (1982). https://doi.org/10.1007/BF00453710

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00453710

Key words

Search

Navigation