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Archives of oto-rhino-laryngology

, Volume 241, Issue 3, pp 295–301 | Cite as

The effects of tympanic neurectomy and chorda tympanectomy on experimentally induced parotid duct fistulae in rabbits

  • R. Chilla
  • F. J. de Paula Lima
  • M. Droese
  • C. Arglebe
Article

Summary

To study the effects of parasympathetic denervation on the secretory activity of parotid fistulae, polyethylene catheters were introduced bilaterally into the parotid main excretory ducts of 10 rabbits, followed by unilateral parasympathectomy performed by segmental resection of the tympanic plexus and the chorda tympani nerve. Although salivary flow from the fistulae of the denervated parotid glands stopped up to 8 days earlier than that from the healthy (control) glands, the effect of parasympathectomy was not strong enough to recommend this operation as the method of choice for the clinical inactivation of persistent parotid fistulae.

Key words

Parotid-duct fistulae Parasympathectomy Denervation Tympanic neurectomy Chorda tympanectomy 

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References

  1. 1.
    Arnold HG, Gross CW (1977) Transtympanic neurectomy: a solution to drooling problems. Dev Med Child Neurol 19:509–513Google Scholar
  2. 2.
    Arulpragasam AC (1967) A syndrome of vertigo and salivary gland enlargement with observations on the aetiology of recurrent parotitis. J Laryngol Otol 81:633–647Google Scholar
  3. 3.
    Babad H, Ben-Zvi R, Bdolah A, Schramm M (1967) The mechanism of enzyme secretion by the cell. 4. Effects of inducers, substrates, and inhibitors on amylase secretion by rat parotid slices. Eur J Biochem 1:96–101Google Scholar
  4. 4.
    Batzri S, Selinger Z (1973) Enzyme secretion mediated by the epinephrine β-receptor in rat parotid slices. J Biol Chem 248:356–360Google Scholar
  5. 5.
    Ceska M, Birath K, Brown B (1969) A new and rapid method for the clinical determination of α-amylase activities in human serum and urine. Optimal conditions. Clin Chim Acta 26:437–444Google Scholar
  6. 6.
    Chilla R (1981) Chirurgie der Nerven im HNO-Bereich: Vegetative Hirnnervenstrukturen. Arch Otorhinolaryngol 231:353–400Google Scholar
  7. 7.
    Chilla R, Brüner M, Arglebe C (1979) Function of submaxillary gland following iatrogenic damage to chorda tympani nerve. Acta Otolaryngol (Stockh) 87:152–155Google Scholar
  8. 8.
    Chilla R, Nicklatsch J, Arglebe C (1982) Late sequelae of iatrogenic damage to chorda tympani nerve. Acta Otolaryngol (Stockh) 94:461–465Google Scholar
  9. 9.
    Friedman WH, Swerdlow RS, Pornarico JM (1974) Tympanic neurectomy: a review and an additional indication for this procedure. Laryngoscope 84:568–577Google Scholar
  10. 10.
    Golding-Wood PH (1962) Tympanic neurectomy. J Laryngol Otol 76:683–693Google Scholar
  11. 11.
    Hashash M, State F, Dessouky HI (1978) Effects of tympanic neurectomy on experimentally induced parotid fistulae. J Laryngol Otol 92:399–402Google Scholar
  12. 12.
    Holmberg J (1971) On the nerves to the parotid gland. In: Emmelin N, Zottermann Y (eds) Oral physiology. Pergamon Press, Oxford, pp 17–19Google Scholar
  13. 13.
    Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–275Google Scholar
  14. 14.
    Mandour MA, El-Sheikh MM, El-Garem F (1976) Tympanic neurectomy for parotid fistula. Arch Otolaryngol 102:327–329Google Scholar
  15. 15.
    McCormack RL (1965) Extended tables of the Wilcoxon matched pair signed rank statistic. J Am Stat Assoc 60:864–871Google Scholar
  16. 16.
    Michel RG, Johnson KA, Patterson CN (1977) Parasympathetic nerve section for control of sialorrhea. Arch Otolaryngol 103:94–97Google Scholar
  17. 17.
    Mitchell GAG (1954) The autonomic nerve supply of the throat, nose and ear. J Laryngol Otol 68:495–516Google Scholar
  18. 18.
    Morgan WR (1974) Parotid duct ligation and tympanic neurectomy in chronic recurrent parotiditis. Arch Otolaryngol 98:179–182Google Scholar
  19. 19.
    Muler M (1953) Fistule parotidienne traitée par résection du nerf auriculo-temporal. Ann Otolaryngol Chir Cervicofac 70:53–54Google Scholar
  20. 20.
    Nichols RD (1977) Surgical treatment of chronic suppurative parotitis. A critical review. Laryngoscope 87:2066–2081Google Scholar
  21. 21.
    Parisier SC, Binder WJ, Blitzer A, Friedman WH, Marowitz WF (1978) Evaluation of tympanic neurectomy for gustatory sweating and benign salivary gland disease. Ear Nose Throat J 57:213–223Google Scholar
  22. 22.
    Schramm M, Selinger Z (1974) The function of α- and β-adrenergic receptors and a cholinergic receptor in the secretory cell of rat parotid gland. In: Ceccarelli B, Clementi F, Meldolesi J (eds) Advances in cytopharmacology, vol 2. Raven Press, New York, pp 29–32Google Scholar
  23. 23.
    Townsend GL, Morimoto AM, Kralemann H (1973) Management of sialorrhea in mentally retarded patients by transtympanic neurectomy. Mayo Clin Proc 48:776–779Google Scholar
  24. 24.
    Vollrath M, Arglebe C, Chilla R (1982) Die Bedeutung der Chorda tympani für die Parotisfunktion. Arch Otorhinolaryngol 236:87–95Google Scholar
  25. 25.
    Wallenborn WMcK (1968) Parotid gland atrophy produced by transtympanic destruction of tympanic plexus. Laryngoscope 78:132–144Google Scholar
  26. 26.
    Wiberg A (1971) Function of the chorda tympani before and after operation for clinical otosclerosis. MD Thesis, University of UmeåGoogle Scholar

Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • R. Chilla
    • 1
  • F. J. de Paula Lima
    • 2
  • M. Droese
    • 3
  • C. Arglebe
    • 2
  1. 1.ENT Clinic, Zentralkrankenhaus St-Jürgen-StraßeBremen 1Federal Republic of Germany
  2. 2.Department of OtorhinolaryngologyUniversity of GöttingenGöttingenFederal Republic of Germany
  3. 3.Department of PathologyUniversity of GöttingenGöttingenFederal Republic of Germany

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