Archives of oto-rhino-laryngology

, Volume 242, Issue 3, pp 315–320 | Cite as

Sclerotic changes around the endolymphatic sac in human temporal bones

  • Noboru Sakai
  • Makoto Igarashi
  • Kazuhiro Ohashi
  • Masanori Ishii


We used light microscopy to study 87 human temporal bones (from 47 cases) with no known otological disorders, and found that certain cases had sclerotic changes around the endolymphatic duct and sac. Changes included fibrosis, hyalinization, psammoma formation, and thickened vascular walls. The findings were subjected to statistical analysis, which indicated that most of the changes could be positively correlated with increases in age.

Key words

Human temporal bone Endolymphatic sac Sclerotic changes Aging Statistical analysis 


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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • Noboru Sakai
    • 1
  • Makoto Igarashi
    • 1
  • Kazuhiro Ohashi
    • 1
  • Masanori Ishii
    • 1
  1. 1.Department of Otorhinolaryngology and Communicative SciencesBaylor College of MedicineHoustonUSA

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