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Tracheal transplantation I. The immunogenic effect of rat tracheal transplants

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Summary

To clarify contradictory information in the literature about the immunogenic effect of the trachea, tracheal transplantations were performed orthotopically and heterotopically in two combinations of inbred rat strains. In all in vivo experiments it was possible to demonstrate a considerable systemic immunisation by transplantation antigens. There were no indications of even slight organospecific immunogenicity of the trachea. Thus, the trachea is subject to the same immunological laws for transplantation as all other tissues.

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Authors and Affiliations

  1. Clinic for Diseases of the Ear, Nose and Throat, Christian-Albrecht-University, Hospitalstrasse 20, D-2300, Kiel, Federal Republic of Germany

    A. Beigel

  2. Department of Immunology, Christian-Albrecht-University, Brunswiker Strasse, D-2300, Kiel, Federal Republic of Germany

    W. Müller-Ruchholtz

Authors
  1. A. Beigel
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  2. W. Müller-Ruchholtz
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In co-operation with SFB 111 of the DFG

Lecture given in part at the 54th Annual Meeting of the German Society for Throat, Nose and Ear Medicine, Head and Neck Surgery, 15–19 May 1983, Lübeck-Travemünde, Federal Republic of Germany

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Beigel, A., Müller-Ruchholtz, W. Tracheal transplantation I. The immunogenic effect of rat tracheal transplants. Arch Otorhinolaryngol 240, 185–192 (1984). https://doi.org/10.1007/BF00453477

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  • DOI: https://doi.org/10.1007/BF00453477

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