Archives of Orthopaedic and Trauma Surgery

, Volume 115, Issue 1, pp 53–58 | Cite as

Tumorous calcinosis: a disease of its own?

  • W. Braun
  • E. Mayr
  • K. Kundel
  • A. Rüter
Clinical and Experimental Forum

Abstract

Tumorous calcinosis has been considered as a disease of its own. A survey of the literature shows that only its clinical and radiological appearances are universally agreed upon, while its epidemiology and etiology are still under discussion. A genetic disorder, recurrent soft-tissue microtrauma and terminal renal failure have been put forward as causes. All of them may lead to a localized or generalized disturbance of the calcium-phosphate metabolism, which in turn could produce tumorous calcinosis. Therefore, tumorous calcinosis should be regarded as a rare manifestation of a metabolic disorder rather than a disease of own.

Keywords

Public Health Renal Failure Genetic Disorder Metabolic Disorder Calcinosis 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Aegerter E, Kirkpatrick JA (1975) Orthopedic diseases. Physiology, pathology, radiology, 4th edn., W.B. Saunders, PhiladelphiaGoogle Scholar
  2. 2.
    Allgayer B, Reiser M, Jäger M (1983) CT-Befunde bei verkalkten Pseudotumoren bei Hämodialysepatienten. Fortschr Rbntgenstr 138:732–735Google Scholar
  3. 3.
    Aprin H, Sinha A (1984) Tumoral calcinosis. Report of a case in a one-year-old child. Clin Orthop 185:83–86Google Scholar
  4. 4.
    aldursson H, Evans EB, Dodge WF, Jackson WT (1969) Tumoral calcinosis with hyperphosphatemia. J Bone Joint Surg [Am] 51:913–925Google Scholar
  5. 5.
    Barton DL, Reeves RJ (1961) Tumoral calcinosis. Report of three cases and review of the literature. Am J Roentgenol 86:351–358Google Scholar
  6. 6.
    Berg D (1972) Tumoral calcinosis. Br J Surg 59:570–571Google Scholar
  7. 7.
    Blattert TR, Weckbach A (1993) Tumoröse Calcinose (Morbus Teutschländer). Chirurg 64:592–594Google Scholar
  8. 8.
    Bogumill GP, Lloyd RJ (1985) Tumoral calcinosis in multiple digits: a case report. J Hand Surg [Am] 10:739–743Google Scholar
  9. 9.
    D'Aboville M (1983) Calcinose tumorale chez une femme blanche. A propos d'une observation. J Radiol 64:429–432Google Scholar
  10. 10.
    Duret MH (1899) Tumours multiples et singulaires des bursa sereuses (endotheliomes, peut-etre d'origine parasitaire). Bull Soc Anat 74:725–731Google Scholar
  11. 11.
    Frame B, Herrere LF, Mitchel DC, Fine G (1971) Massive osteolysis and tumoral calcinosis. Am J Med 50:408–412Google Scholar
  12. 12.
    Ghormley RK, Manning GF, Power MH, McCary WE (1942) Mulitple calcified bursae and calcified cysts in soft tissue. Trans West Surg Assoc 51:292Google Scholar
  13. 13.
    Giard CR (1898) cited by Palmer PES (1966) Tumoral calcinosis. Br J Radiol 39:518–525Google Scholar
  14. 14.
    Gregorsiewicz A, Warda E (1989) Tumoral calcinosis: successful medical treatment. J Bone Joint Surg [Am] 71:1244–1248Google Scholar
  15. 15.
    Harkess JW, Peters HJ (1967) Tumoral calcinosis. J Bone Joint Surg [Am] 49:721–731Google Scholar
  16. 16.
    Hutter RVP, Foote FW, Francis KC, Higinbothan NL (1962) Parosteal fasciitis. Am J Surg 104:800–807Google Scholar
  17. 17.
    Inclan A, Leon P, (1943) Tumoral calcinosis. J Am Med Assoc 121:490–1195Google Scholar
  18. 18.
    Janda J (1986) Sekundärer Hyperparathyreoidismus bei langfristig hämodialysierten Patienten. Zentralbl Allg Pathol 132:523–531Google Scholar
  19. 19.
    Kirk TS, Simon MA (1981) Tumoral calcinosis. J Bone Joint Surg [Am] 63:1167–1169Google Scholar
  20. 20.
    Knowles SAS, Declerck G, Anthony PP (1983) Tumoral calcinosis. Br J Surg 70:105–107Google Scholar
  21. 21.
    Kolawole TM, Bohrer SP (1974) Tumoral calcinosis with ‘fluid levels’ in the tumoral masses. Am J Roentgenol 120:461–465Google Scholar
  22. 22.
    Lafferty FW, Reynolds ES, Pearson OM (1965) Tumoral calcinosis: a metabolic disease of obscure etiology. Am J Med 38:105–118Google Scholar
  23. 23.
    Lange H, Gossmann HH (1967) Metastatische Verkalkungen während Peritonealdialyse im Terminalstadium einer chronischen Glomerulonephritis. Dtsch Med Wochenschr 92:296–300Google Scholar
  24. 24.
    Levin RT, Genovesse PD (1959) Report of a case of longstanding renal insufficiency with extensive metabolic calcification (renal osteitis fibrosa cystica). Am J Roentgenol 64:423–427Google Scholar
  25. 25.
    McClatchie S, Bremner AD (1969) Tumoral calcinosis — an unrecognized disease. Br Med J 1:153–156Google Scholar
  26. 26.
    McKee PH, Liomba NG, Hott MRS (1982) Tumoral calcinosis, a pathological study of fifty six cases. Br J Dermatol 107:669–674Google Scholar
  27. 27.
    Mitnick PD, Goldfarb S, Slatopolsky E, Lemann J, Gray RW, Angus ZS (1989) Calcium and phosphate metabolism in tumoral calcinosis. Ann Intern Med 92:482–487Google Scholar
  28. 28.
    Mohr W (1984) Arthropathien. In: Aufdermaur M, Baur E, Fassbender HG, Geiler G, Höpker WW, Meister HP, Mohr W, Stiehl P, Thumer J, Tillmann B, Töndury G (eds) Pathologie der Gelenke and Weichteiltumoren. Springer, Berlin Heidelberg New YorkGoogle Scholar
  29. 29.
    Mozaffarian G, Lafferty FW, Pearson OH (1972) Treatment of tumoral calcinosis with phosphorous deprivation. Ann Intern Med 77:741–745Google Scholar
  30. 30.
    Palmer PES (1966) Tumoral calcinosis. Br J Radiol 39:518–525Google Scholar
  31. 31.
    Prasad VLN, Naresh KN, Govind-Krishna SR, Ananthakrishnan N, Veliath AJ (1989) Tumoral calcinosis. World J Surg 13:803–808Google Scholar
  32. 32.
    Reed RJ, Hunt RW (1965) Granulomatous (tumoural) calcinosis. Clin Orthop 43:233–240Google Scholar
  33. 33.
    Ritz E, Kuhn HM, Krempien P, Beduhn D (1973) Röntgenologische Zeichen des gestörten Kalziumstoffwechsels bei Dialysepatienten. 1. Häufigkeit röntgenologischer Skelettveränderungen. Fortschr Rontgenstr 119:52–63Google Scholar
  34. 34.
    Rupf G, Jansen T, Weller S (1990) Morbus Teutschländer - Eine seltene benigne Weichteilerkrankung. Fallbeschreibung. Akt Traumatol 20:144–147Google Scholar
  35. 35.
    Seifert G (1980) Extraossäre Verkalkungen und ektopische Knochenbildungen. In: Kuhlencordt F, Bartelheimer H (eds) Klinische Osteologie. Springer, Berlin Heidelberg New YorkGoogle Scholar
  36. 36.
    Selye H (1962) Calciphylaxis. University of Chicago Press, Chicago, p332Google Scholar
  37. 37.
    Slavin G, Klenerman L, Darby A, Bansel S (1973) Tumoral calcinosis in England. Br J Med 1:147–150Google Scholar
  38. 38.
    Smit GG, Schmamann A (1967) Tumoral calcinosis. J Bone Joint Surg [Br] 49:698–703Google Scholar
  39. 39.
    Suzuki K, Takahashi S, Ito K (1979) Tumoral calcinosis in a patient undergoing hemodialysis. Acta Orthop Scand 50:27–31Google Scholar
  40. 40.
    Teutschländer O (1943) Über progressive Lipogranulomatose der Muskulatur. Zugleich em Beitrag zur Pathogenese der Myopathia osteoplastica progressiva. Klin Wochenschr 13:451–453Google Scholar
  41. 41.
    Teutschländer O (1951) Zur Kenntnis der lipoido-calcinosis progrediens. Zentralbl Allg Pathol 87:1–3Google Scholar
  42. 42.
    Thomson JEM, Tanner FJ (1949) Tumoral calcinosis. J Bone Joint Surg [Am] 31:132–140Google Scholar
  43. 43.
    Thomson JG (1966) Calcifying collagenolysis (tumoral calcinosis) Br J Radiol 39:526–530Google Scholar
  44. 44.
    Unanue ER, Allen PM (1987) The basis for the immunoregulatory role of macrophages and other accessory cells. Science 236:43–48Google Scholar
  45. 45.
    Vasudev KS, Tapp E, Harris M (1973) Tumoral calcinosis in Britain. Br Med J 1:676–679Google Scholar
  46. 46.
    Veress B, Malik MOA, El Hassan AM (1975) Tumoral lipocalcinosis: a clinicopathological study of 20 cases. J Pathol 119:113–117Google Scholar
  47. 47.
    Viegas SF, Evans EB, Calhoun J, Goodwiller SE (1985) Tumoral calcinosis: a case report and review of literature. J Hand Surg [Am] 10:744–748Google Scholar

Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • W. Braun
    • 1
  • E. Mayr
    • 1
  • K. Kundel
    • 1
  • A. Rüter
    • 1
  1. 1.Klinik fur Unfall- und WiederherstellungschirurgieZentralklinikum AugsburgAugsburgGermany

Personalised recommendations