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Calcitonin, estradiol, and hydroxyproline as parameters in the early diagnosis of involutional osteoporosis

The importance of the “second calcitoni”

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Summary

Bone metabolism was studied in a group of 92 subjects. A greater age-related decrease in calcitonin and estradiol concentrations exists in women than in men, though this difference was not significant; it was significant, however, when the values of the three different groups of women were compared. We present what we have called the second calcitonin phenomenon, that is, a highly significant difference in women between a second basal calcitonin level and the primary admission value. In the calcium infusion test, men considered to be osteoporotic showed a deceleration in the rapid loss of reserve calcitonin deposits.

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Authors and Affiliations

  1. Department of Traumatology and Orthopedic Surgery, Hospital Clfnico Universitario, Salamanca, Spain

    L. Ferrández

  2. Hospital “Virgen Blanca”, Leon, Spain

    M. Martín & M. Fernández

Authors
  1. L. Ferrández
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  2. M. Martín
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  3. M. Fernández
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Ferrández, L., Martín, M. & Fernández, M. Calcitonin, estradiol, and hydroxyproline as parameters in the early diagnosis of involutional osteoporosis. Arch Orthop Trauma Surg 109, 181–185 (1990). https://doi.org/10.1007/BF00453137

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